Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNK | O75909 | 2/20 | 0.67 |
| ▸ | CCND3 | P30281 | 2/20 | 0.67 |
| ▸ | CDK9 | P50750 | 2/20 | 0.67 |
| ▸ | CDK6 | Q00534 | 2/20 | 0.67 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.67 |
| ▸ | CDK2 | P24941 | 1/20 | 0.67 |
| ▸ | PKMYT1 | Q99640 | 2/20 | 0.66 |
| ▸ | BRD4 | O60885 | 4/20 | 0.66 |
| ▸ | SYK | P43405 | 1/20 | 0.63 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.62 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.61 |
| ▸ | JAK3 | P52333 | 1/20 | 0.60 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.60 |
| ▸ | IGF1R | P08069 | 2/20 | 0.60 |
| ▸ | INSR | P06213 | 1/20 | 0.60 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.60 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.60 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.59 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.59 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19203832 | 0.85 | FGFR1 (0.64) | BRD4SYKALKIGF1REGFR | |
| SCHEMBL11916428 | 0.83 | CCNK (0.65) | CCNKCCND3CDK9CDK6CCNA2 | |
| SCHEMBL23704665 | 0.81 | CCNK (0.65) | CCNKCCND3CDK9CDK6CCNA2 | |
| SCHEMBL30394638 | 0.81 | CCNA2 (1.00) | CCNKCCND3CDK9CDK6CCNA2 | |
| SCHEMBL30395224 | 0.80 | CCND3 (1.00) | CCNKCCND3CDK9CDK6CCNA2 | |
| SCHEMBL23704673 | 0.80 | PKMYT1 (0.69) | CCNKCCND3CDK9CDK6CCNA2 | |
| SCHEMBL2061358 | 0.80 | MAPT (0.62) | CCNKCCND3CDK9CDK6CCNA2 | |
| SCHEMBL11915885 | 0.79 | PKMYT1 (0.74) | CCNKCCND3CDK9CDK6CCNA2 | |
| SCHEMBL30306485 | 0.79 | BRD4 (1.00) | CCNKCCND3CDK9CDK6CCNA2 | |
| SCHEMBL17526171 | 0.79 | BRD4 (1.00) | CCNKCCND3CDK9CDK6CCNA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170218000-A1 | PHOSPHOROUS DERIVATIVES AS KINASE INHIBITORS | ARIAD PHARMACEUTICALS, INC. | 2017-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170218000-A1 | PHOSPHOROUS DERIVATIVES AS KINASE INHIBITORS | MAP3K6, PIK3CA, MAP3K20 | CCNK 393/4885CCND3 1243/4885CDK9 60/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.