Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | GBA1 | P04062 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22129037 | 0.77 | MAPK1 (0.41) | MAPK1ALDH1A1 | |
| SCHEMBL13451765 | 0.77 | MAPK1 (0.32) | MAPK1 | |
| SCHEMBL9937807 | 0.76 | MAPK1 (0.44) | MAPK1KMT2AGBA1KDM4EALDH1A1 | |
| SCHEMBL26110659 | 0.76 | TSHR (0.33) | — | |
| SCHEMBL3324237 | 0.76 | TSHR (0.33) | — | |
| SCHEMBL31665062 | 0.76 | TSHR (0.33) | — | |
| SCHEMBL13451555 | 0.76 | SLC18A3 (0.33) | KMT2AHSD11B1SLC18A3 | |
| SCHEMBL21772146 | 0.76 | MAPK1 (0.50) | MAPK1HSD11B1KDM4EALDH1A1 | |
| SCHEMBL22117940 | 0.76 | MAPK1 (0.50) | MAPK1HSD11B1KDM4EALDH1A1 | |
| SCHEMBL3462061 | 0.76 | MAPK1 (0.50) | MAPK1HSD11B1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2326327-A2 | ANALOGS OF INDOLE-3-CARBINOL AND THEIR USE AS AGENTS AGAINST INFECTION | SRI International (US) | 2011-06-01 | — | — | EP | disclosed |
| WO-2010033198-A2 | ANALOGS OF INDOLE-3-CARBINOL AND THEIR USE AS AGENTS AGAINST INFECTION | SRI INTERNATIONAL (US) | 2010-03-25 | — | — | WO | disclosed |