Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 8/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | TP53 | P04637 | 3/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL37396 | 0.98 | TSHR (0.45) | TSHRHCAR2HPGDLMNAALDH1A1 | |
| SCHEMBL2184214 | 0.98 | TSHR (0.45) | TSHRHCAR2HPGDLMNAALDH1A1 | |
| SCHEMBL10953217 | 0.95 | TSHR (0.43) | TSHRHCAR2HPGDLMNAALDH1A1 | |
| SCHEMBL1919371 | 0.95 | TSHR (0.43) | TSHRHCAR2HPGDLMNAALDH1A1 | |
| SCHEMBL28190611 | 0.95 | TSHR (0.43) | TSHRHCAR2HPGDLMNAALDH1A1 | |
| SCHEMBL183980 | 0.95 | TSHR (0.43) | TSHRHCAR2HPGDLMNAALDH1A1 | |
| SCHEMBL1919847 | 0.95 | TSHR (0.43) | TSHRHCAR2HPGDLMNAALDH1A1 | |
| SCHEMBL184163 | 0.95 | TSHR (0.43) | TSHRHCAR2HPGDLMNAALDH1A1 | |
| SCHEMBL1919547 | 0.95 | TSHR (0.43) | TSHRHCAR2HPGDLMNAALDH1A1 | |
| SCHEMBL19046763 | 0.90 | TSHR (0.44) | TSHRHCAR2HPGDALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8709705-B2 | Metal-containing compositions and method of making same | PRYOG, LLC (US) | 2014-04-29 | — | — | US | claimed |
| US-20120315451-A1 | Metal-Containing Compositions and Method of Making Same | PRYOG LLC | 2012-12-13 | — | — | US | claimed |
| US-8802346-B2 | Metal compositions and methods of making same | PRYOG, LLC (US) | 2014-08-12 | — | — | US | disclosed |
| US-8709705-B2 | Metal-containing compositions and method of making same | PRYOG, LLC (US) | 2014-04-29 | — | — | US | disclosed |
| US-20120315451-A1 | Metal-Containing Compositions and Method of Making Same | PRYOG LLC | 2012-12-13 | — | — | US | disclosed |
| US-20110184139-A1 | METAL COMPOSITIONS AND METHODS OF MAKING SAME | PRYOG, LLC | 2011-07-28 | — | — | US | disclosed |
| EP-2326744-A1 | METAL COMPOSITIONS AND METHODS OF MAKING SAME | Pryog LLC (US) | 2011-06-01 | — | — | EP | disclosed |
| WO-2010059174-A1 | METAL COMPOSITIONS AND METHODS OF MAKING SAME | PRYOG, LLC (US) | 2010-05-27 | — | — | WO | disclosed |