Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 20/20 | 0.80 |
| ▸ | JAK1 | P23458 | 20/20 | 0.80 |
| ▸ | JAK3 | P52333 | 19/20 | 0.80 |
| ▸ | TYK2 | P29597 | 2/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19205840 | 1.00 | JAK2 (0.80) | JAK2JAK1JAK3TYK2 | |
| Maleic Acid SCHEMBL28633209 | 0.92 | JAK2 (0.69) | JAK2JAK1JAK3TYK2 | |
| SCHEMBL12545726 | 0.91 | JAK2 (0.80) | JAK2JAK1JAK3TYK2 | |
| SCHEMBL19205842 | 0.90 | JAK2 (0.78) | JAK2JAK1JAK3TYK2 | |
| SCHEMBL22315093 | 0.90 | JAK2 (0.78) | JAK2JAK1JAK3TYK2 | |
| SCHEMBL22315101 | 0.90 | JAK2 (0.78) | JAK2JAK1JAK3TYK2 | |
| SCHEMBL22314980 | 0.90 | JAK2 (0.78) | JAK2JAK1JAK3TYK2 | |
| SCHEMBL22314985 | 0.90 | JAK2 (0.78) | JAK2JAK1JAK3TYK2 | |
| SCHEMBL2015696 | 0.90 | JAK2 (0.78) | JAK2JAK1JAK3TYK2 | |
| SCHEMBL2015700 | 0.90 | JAK2 (0.78) | JAK2JAK1JAK3TYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9926327-B2 | Process for preparing 7H-pyrrolo[2,3-D]pyrimidine compounds | ZOETIS SERVICES LLC (US) | 2018-03-27 | — | — | US | disclosed |
| US-20170233397-A1 | PROCESS FOR PREPARING 7H-PYRROLO[2,3-D]PYRIMIDINE COMPOUNDS | ZOETIS SERVICES LLC | 2017-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170233397-A1 | PROCESS FOR PREPARING 7H-PYRROLO[2,3-D]PYRIMIDINE COMPOUNDS | TPMT, TYMS, TYMP | JAK2 603/4885JAK1 353/4885JAK3 266/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.