Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 10/20 | 0.79 |
| ▸ | SLC6A4 | P31645 | 10/20 | 0.79 |
| ▸ | SLC6A3 | Q01959 | 10/20 | 0.79 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | MLNR | O43193 | 1/20 | 0.56 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.56 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.56 |
| ▸ | ESR1 | P03372 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.56 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.56 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.56 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | HTR1A | P08908 | 1/20 | 0.56 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22398922 | 0.90 | SLC6A2 (0.80) | SLC6A2SLC6A4SLC6A3MEN1KMT2A | |
| SCHEMBL20690372 | 0.90 | SLC6A2 (0.80) | SLC6A2SLC6A4SLC6A3MEN1KMT2A | |
| SCHEMBL6554028 | 0.87 | SLC6A4 (0.80) | SLC6A2SLC6A4SLC6A3MEN1KMT2A | |
| SCHEMBL6946811 | 0.87 | SLC6A2 (0.65) | SLC6A2SLC6A4SLC6A3MEN1KMT2A | |
| SCHEMBL10995616 | 0.86 | SLC6A2 (0.76) | SLC6A2SLC6A4SLC6A3MEN1KMT2A | |
| SCHEMBL11133286 | 0.86 | SLC6A2 (0.76) | SLC6A2SLC6A4SLC6A3MEN1KMT2A | |
| SCHEMBL9843400 | 0.86 | SLC6A2 (0.76) | SLC6A2SLC6A4SLC6A3MEN1KMT2A | |
| SCHEMBL11133547 | 0.86 | SLC6A2 (0.76) | SLC6A2SLC6A4SLC6A3MEN1KMT2A | |
| SCHEMBL6944959 | 0.86 | SLC6A2 (0.76) | SLC6A2SLC6A4SLC6A3MEN1KMT2A | |
| SCHEMBL8253409 | 0.86 | SLC6A2 (0.76) | SLC6A2SLC6A4SLC6A3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4337182-A1 | REDUCING SIDE EFFECTS OF NMDA RECEPTOR ANTAGONISTS | Seelos Therapeutics, Inc. (US) | 2024-03-20 | — | — | EP | disclosed |
| EP-4277635-A1 | MODIFIED MIR-135, CONJUGATED FORM THEREOF, AND USES OF SAME | Yeda Research and Development Co. Ltd (IL) | 2023-11-22 | — | — | EP | disclosed |
| WO-2022153322-A1 | MODIFIED MIR-135, CONJUGATED FORM THEREOF, AND USES OF SAME | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2022-07-21 | — | — | WO | disclosed |
| EP-3472192-A1 | SPIDER VENOM PEPTIDES AND METHODS OF USE FOR MODULATING SODIUM CHANNELS. | The University of Queensland (AU) | 2019-04-24 | — | — | EP | disclosed |
| EP-3411040-A1 | SMALL MOLECULES FOR MOUSE SATELLITE CELL PROLIFERATION | President and Fellows of Harvard College (US) | 2018-12-12 | — | — | EP | disclosed |
| WO-2017219081-A1 | SPIDER VENOM PEPTIDES AND METHODS OF USE FOR MODULATING SODIUM CHANNELS. | THE UNIVERSITY OF QUEENSLAND (AU) | 2017-12-28 | — | — | WO | disclosed |
| WO-2017136480-A1 | SMALL MOLECULES FOR MOUSE SATELLITE CELL PROLIFERATION | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2017-08-10 | — | — | WO | disclosed |