Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8914369 | 0.74 | KDM4E (0.42) | USP2TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL4685763 | 0.72 | USP2 (0.40) | USP2TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL10894498 | 0.70 | USP2 (0.39) | USP2TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL5595029 | 0.69 | TSHR (0.48) | USP2TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL10894245 | 0.67 | TSHR (0.39) | USP2TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL10894476 | 0.67 | USP2 (0.36) | USP2TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL14777136 | 0.67 | KDM4E (0.36) | USP2TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL10896547 | 0.66 | TSHR (0.39) | USP2TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL11697628 | 0.65 | — | — | |
| SCHEMBL7187604 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107709288-A | Phosphamide derivative and preparation method and application thereof | 四川海思科制药有限公司 | 2018-02-16 | — | — | CN | disclosed |
| WO-2017133517-A1 | PHOSPHAMIDE DERIVATIVE, METHOD FOR MANUFACTURING THE SAME, AND USES THEREOF | 四川海思科制药有限公司 | 2017-08-10 | — | — | WO | disclosed |
| WO-2017133517-A1 | PHOSPHAMIDE DERIVATIVE, METHOD FOR MANUFACTURING THE SAME, AND USES THEREOF | 四川海思科制药有限公司 | 2017-08-10 | — | — | WO | disclosed |