Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | NAMPT | P43490 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | VNN1 | O95497 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SPR | P35270 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30089199 | 0.84 | NAMPT (0.48) | HPGDSHDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL1265671 | 0.84 | NAMPT (0.48) | HPGDSHDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL29602711 | 0.82 | NPSR1 (0.50) | HPGDSHDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL3003567 | 0.82 | NPSR1 (0.50) | HPGDSHDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL1933893 | 0.80 | HDAC3 (0.51) | HPGDSHDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL9245 | 0.79 | HDAC3 (0.48) | HPGDSHDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL23022741 | 0.79 | HDAC3 (0.50) | HPGDSHDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL21246171 | 0.79 | RECQL (0.53) | HPGDSHDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL3003564 | 0.79 | HDAC3 (0.50) | HPGDSHDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL29884167 | 0.79 | RECQL (0.53) | HPGDSHDAC3HDAC1HDAC2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2699557-B1 | 3-(OXAZOL-2-YL-ETHOXY)- AND 3-(THIAZOL-2-YL-ETHOXY)-BENZAMIDE DERIVATIVES AS ANTI-BACTERIAL AGENTS | BIOTA SCIENT MANAGEMENT (AU) | 2017-08-16 | — | — | EP | claimed |
| WO-2020023793-A1 | PEGYLATED PRODRUGS OF PHENOLIC TRPV1 AGONISTS | Concentric Analgesics, Inc. (US) | 2020-01-30 | — | — | WO | disclosed |