⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8692978 | 0.98 | — | — | |
| SCHEMBL7021307 | 0.67 | — | — | |
| SCHEMBL28202715 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL7273267 | 0.66 | — | — | |
| SCHEMBL1008670 | 0.65 | — | — | |
| SCHEMBL4629715 | 0.64 | — | — | |
| SCHEMBL28514555 | 0.64 | — | — | |
| Ethylamine SCHEMBL28802570 | 0.64 | — | — | |
| Hydrochloric Acid SCHEMBL27523505 | 0.62 | — | — | |
| Ammonia Solution, Strong SCHEMBL27818154 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220389492-A1 | RNA Fixation and Detection in CLARITY-based Hydrogel Tissue | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2022-12-08 | — | — | US | claimed |
| US-11254974-B2 | RNA fixation and detection in clarity-based hydrogel tissue | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2022-02-22 | — | — | US | claimed |
| CN-108210932-B | Preparation method of charge-driven self-assembled chitosan-based drug-loaded nanoparticles | 温州医科大学 | 2020-06-30 | — | — | CN | claimed |
| US-20190119735-A1 | RNA Fixation and Detection in CLARITY-based Hydrogel Tissue | THE BOARD OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2019-04-25 | — | — | US | claimed |
| EP-4339956-A2 | MULTIPLEXED IMAGING USING MERFISH, EXPANSION MICROSCOPY, AND RELATED TECHNOLOGIES | President and Fellows of Harvard College (US) | 2024-03-20 | — | — | EP | disclosed |
| EP-3538867-B1 | MULTIPLEXED IMAGING USING MERFISH, EXPANSION MICROSCOPY, AND RELATED TECHNOLOGIES | HARVARD COLLEGE (US) | 2024-01-03 | — | — | EP | disclosed |
| US-20220389492-A1 | RNA Fixation and Detection in CLARITY-based Hydrogel Tissue | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2022-12-08 | — | — | US | disclosed |
| US-11254974-B2 | RNA fixation and detection in clarity-based hydrogel tissue | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2022-02-22 | — | — | US | disclosed |
| CN-108210932-B | Preparation method of charge-driven self-assembled chitosan-based drug-loaded nanoparticles | 温州医科大学 | 2020-06-30 | — | — | CN | disclosed |
| EP-3538867-A1 | MULTIPLEXED IMAGING USING MERFISH, EXPANSION MICROSCOPY, AND RELATED TECHNOLOGIES | President and Fellows of Harvard College (US) | 2019-09-18 | — | — | EP | disclosed |
| US-20190276881-A1 | MULTIPLEXED IMAGING USING MERFISH, EXPANSION MICROSCOPY, AND RELATED TECHNOLOGIES | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2019-09-12 | — | — | US | disclosed |
| CN-110168346-A | Multiplex imaging using MERISH, extended microscopy and related techniques | 哈佛学院院长及董事 | 2019-08-23 | — | — | CN | disclosed |
| US-20190119735-A1 | RNA Fixation and Detection in CLARITY-based Hydrogel Tissue | THE BOARD OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2019-04-25 | — | — | US | disclosed |
| CN-108210932-A | A kind of preparation method of charge driving self-assembly chitosan base medicine-carried nano particles | 温州医科大学 | 2018-06-29 | — | — | CN | disclosed |
| WO-2018089438-A1 | MULTIPLEXED IMAGING USING MERFISH, EXPANSION MICROSCOPY, AND RELATED TECHNOLOGIES | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2018-05-17 | — | — | WO | disclosed |
| WO-2017139501-A1 | RNA FIXATION AND DETECTION IN CLARITY-BASED HYDROGEL TISSUE | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2017-08-17 | — | — | WO | disclosed |