Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 16/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 15/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.39 |
| ▸ | KDM1A | O60341 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1604873 | 0.85 | MEN1 (0.53) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL5037731 | 0.79 | MEN1 (0.55) | MEN1KMT2AKDM4E | |
| SCHEMBL1604853 | 0.79 | MEN1 (0.49) | MEN1KMT2AKDM4EALDH1A1PIK3CD | |
| SCHEMBL1605074 | 0.75 | MEN1 (0.45) | MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL12710412 | 0.74 | KDM4E (0.72) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL1604052 | 0.74 | MEN1 (0.70) | MEN1KMT2AKDM4EALDH1A1KDM1A | |
| SCHEMBL1604737 | 0.71 | MEN1 (0.50) | MEN1KMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL1921562 | 0.70 | KDM4E (0.51) | MEN1KMT2AKDM4E | |
| SCHEMBL1604871 | 0.70 | MEN1 (0.52) | MEN1KMT2AKDM4E | |
| SCHEMBL1604971 | 0.70 | MEN1 (0.49) | MEN1KMT2AKDM4EKDM1AMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1622914-B1 | NEW PIPERIDINYLAMINO-THIENO[2,3-D] PYRIMIDINE COMPOUNDS | TROVIS PHARMACEUTICALS LLC (US) | 2011-06-01 | — | — | EP | disclosed |