Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR4 | O95977 | 2/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.42 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.37 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ENO1 | P06733 | 2/20 | 0.31 |
| ▸ | INPP5A | Q14642 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19212088 | 0.86 | GRM4 (0.39) | S1PR4S1PR1S1PR3GRM4S1PR5 | |
| SCHEMBL4954695 | 0.86 | — | — | |
| SCHEMBL15031187 | 0.81 | S1PR4 (0.41) | S1PR4S1PR1S1PR3GRM4S1PR5 | |
| SCHEMBL20843659 | 0.81 | S1PR4 (0.37) | S1PR4S1PR1S1PR3GRM4S1PR5 | |
| SCHEMBL4255645 | 0.81 | S1PR4 (0.37) | S1PR4S1PR1S1PR3GRM4S1PR5 | |
| SCHEMBL6422222 | 0.77 | S1PR4 (0.50) | S1PR4S1PR1S1PR3S1PR5MMP2 | |
| SCHEMBL11662090 | 0.77 | S1PR4 (0.35) | S1PR4S1PR1S1PR3S1PR5 | |
| Phosphonic Acid SCHEMBL9538179 | 0.75 | S1PR4 (0.34) | S1PR4S1PR1S1PR3 | |
| SCHEMBL12958903 | 0.75 | S1PR4 (0.38) | S1PR4S1PR1S1PR3S1PR5MMP2 | |
| SCHEMBL22869419 | 0.75 | S1PR4 (0.45) | S1PR4S1PR1S1PR3S1PR5INPP5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3413934-A1 | IMPROVED TREATMENT OF IMPLANTS WITH PHOSPHONIC ACID COMPOUNDS | Nano Bridging Molecules SA (CH) | 2018-12-19 | — | — | EP | claimed |
| WO-2017137623-A1 | IMPROVED TREATMENT OF IMPLANTS WITH PHOSPHONIC ACID COMPOUNDS | NANO BRIDGING MOLECULES SA (CH) | 2017-08-17 | — | — | WO | claimed |