SCHEMBL19212015

SCHEMBL19212015

O=P(O)(O)C=CCC(CCCP(=O)(O)O)(P(=O)(O)O)P(=O)(O)O

nearest known ligand 0.39

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
GGPS1 O95749 2/20 0.39
TYMS P04818 1/20 0.38
LMNA P02545 1/20 0.33
CYP3A4 P08684 1/20 0.33
NFKB1 P19838 1/20 0.33
BLM P54132 1/20 0.33
PMP22 Q01453 1/20 0.33
LPAR3 Q9UBY5 3/20 0.31
LPAR2 Q9HBW0 1/20 0.31
BBOX1 O75936 1/20 0.31
GRM4 Q14833 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19212012 1.00 GGPS1 (0.39) GGPS1TYMSLMNACYP3A4NFKB1
SCHEMBL20699850 0.95 GGPS1 (0.39) GGPS1TYMSLMNACYP3A4NFKB1
SCHEMBL20699851 0.95 GGPS1 (0.39) GGPS1TYMSLMNACYP3A4NFKB1
SCHEMBL19212076 0.81 GGPS1 (0.43) GGPS1TYMSLMNACYP3A4NFKB1
SCHEMBL19212075 0.81 GGPS1 (0.43) GGPS1TYMSLMNACYP3A4NFKB1
SCHEMBL2318641 0.78 TYMS (0.55) GGPS1TYMSLMNACYP3A4NFKB1
SCHEMBL19212073 0.77 GGPS1 (0.41) GGPS1TYMSLMNACYP3A4NFKB1
SCHEMBL19212078 0.77 GGPS1 (0.41) GGPS1TYMSLMNACYP3A4NFKB1
SCHEMBL19212014 0.74 GGPS1 (0.56) GGPS1TYMSLMNACYP3A4NFKB1
SCHEMBL2319390 0.72 GGPS1 (0.58) GGPS1TYMSLMNACYP3A4NFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3413934-B1 IMPROVED TREATMENT OF IMPLANTS WITH PHOSPHONIC ACID COMPOUNDS NANO BRIDGING MOLECULES SA (CH) 2021-10-13 EP claimed
CN-109195641-B Improved implant treatment with phosphonic acid compounds 纳米桥接分子股份公司 2021-07-27 CN claimed
US-11000627-B2 Treatment of implants with phosphonic acid compounds NANO BRIDGING MOLECULES SA (CH) 2021-05-11 US claimed
US-20190038802-A1 IMPROVED TREATMENT OF IMPLANTS WITH PHOSPHONIC ACID COMPOUNDS NANO BRIDGING MOLECULES SA (CH) 2019-02-07 US claimed
EP-3413934-B1 IMPROVED TREATMENT OF IMPLANTS WITH PHOSPHONIC ACID COMPOUNDS NANO BRIDGING MOLECULES SA (CH) 2021-10-13 EP disclosed
CN-109195641-B Improved implant treatment with phosphonic acid compounds 纳米桥接分子股份公司 2021-07-27 CN disclosed
US-11000627-B2 Treatment of implants with phosphonic acid compounds NANO BRIDGING MOLECULES SA (CH) 2021-05-11 US disclosed
US-20190038802-A1 IMPROVED TREATMENT OF IMPLANTS WITH PHOSPHONIC ACID COMPOUNDS NANO BRIDGING MOLECULES SA (CH) 2019-02-07 US disclosed
EP-3413934-A1 IMPROVED TREATMENT OF IMPLANTS WITH PHOSPHONIC ACID COMPOUNDS Nano Bridging Molecules SA (CH) 2018-12-19 EP disclosed
WO-2017137623-A1 IMPROVED TREATMENT OF IMPLANTS WITH PHOSPHONIC ACID COMPOUNDS NANO BRIDGING MOLECULES SA (CH) 2017-08-17 WO disclosed