Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 8/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.47 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.45 |
| ▸ | ADK | P55263 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16004606 | 0.86 | GRM5 (0.57) | GRM5KCNH2CYP1A2 | |
| SCHEMBL30526535 | 0.86 | GRM5 (0.57) | GRM5KCNH2CYP1A2 | |
| SCHEMBL352291 | 0.81 | GRM5 (0.65) | GRM5KCNH2TDP1CYP1A2 | |
| SCHEMBL18343633 | 0.80 | PTGDR2 (0.43) | GRM5KCNH2PTGDR2CYP1A2ADK | |
| SCHEMBL30707788 | 0.78 | KCNH2 (0.61) | GRM5KCNH2PTGDR2CYP1A2 | |
| SCHEMBL4448140 | 0.78 | KCNH2 (0.61) | GRM5KCNH2PTGDR2CYP1A2 | |
| SCHEMBL12424795 | 0.77 | GRM5 (0.55) | GRM5KCNH2CYP1A2 | |
| SCHEMBL1696992 | 0.77 | GRM5 (0.58) | GRM5KCNH2CYP1A2 | |
| SCHEMBL30521907 | 0.77 | GRM5 (0.49) | GRM5KCNH2CYP1A2 | |
| Methyl Alcohol SCHEMBL28902013 | 0.77 | GRM5 (0.67) | GRM5KCNH2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108794385-B | Method for synthesizing phenylethynyl pyridine derivative | 陕西师范大学 | 2021-09-21 | — | — | CN | disclosed |
| US-9935277-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2018-04-03 | — | — | US | disclosed |
| US-9935277-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2018-04-03 | — | — | US | disclosed |
| US-9935277-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2018-04-03 | — | — | US | disclosed |
| US-20150214494-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION | 2015-07-30 | — | — | US | disclosed |
| US-20150214494-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION | 2015-07-30 | — | — | US | disclosed |
| US-20150214494-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION | 2015-07-30 | — | — | US | disclosed |
| US-8283476-B2 | Transition metal catalyzed synthesis of 2H-indazoles | SANOFI (FR) | 2012-10-09 | — | — | US | disclosed |
| EP-2134682-B1 | A TRANSITION METAL CATALYZED SYNTHESIS OF N-AMINOINDOLES | SANOFI SA (FR) | 2011-12-14 | — | — | EP | disclosed |
| US-8026375-B2 | Transition metal catalyzed synthesis of N-aminoindoles | SANOFI-AVENTIS (FR) | 2011-09-27 | — | — | US | disclosed |
| EP-2170833-B1 | A TRANSITION METAL CATALYZED SYNTHESIS OF 2H-INDAZOLES | SANOFI AVENTIS (FR) | 2011-06-01 | — | — | EP | disclosed |
| US-20100234601-A1 | Transition metal catalyzed synthesis of 2H-indazoles | SANOFI-AVENTIS (FR) | 2010-09-16 | — | — | US | disclosed |
| US-20100168429-A1 | Transition metal catalyzed synthesis of N-aminoindoles | SANOFI-AVENTIS (FR) | 2010-07-01 | — | — | US | disclosed |
| EP-2170833-A1 | A TRANSITION METAL CATALYZED SYNTHESIS OF 2H-INDAZOLES | Sanofi-Aventis (FR) | 2010-04-07 | — | — | EP | disclosed |
| EP-2134682-A1 | A TRANSITION METAL CATALYZED SYNTHESIS OF N-AMINOINDOLES | Sanofi-Aventis (FR) | 2009-12-23 | — | — | EP | disclosed |
| WO-2009000411-A1 | A TRANSITION METAL CATALYZED SYNTHESIS OF 2H-INDAZOLES | SANOFI-AVENTIS (FR) | 2008-12-31 | — | — | WO | disclosed |
| WO-2008125207-A1 | A TRANSITION METAL CATALYZED SYNTHESIS OF N-AMINOINDOLES | SANOFI-AVENTIS (FR) | 2008-10-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100168429-A1 | Transition metal catalyzed synthesis of N-aminoindoles | NAT1, H1-3, H1-2 | GRM5 2965/4885KCNH2 177/4885PTGDR2 1904/4885 |
| US-20100234601-A1 | Transition metal catalyzed synthesis of 2H-indazoles | H1-3, H1-2, H1-4 | GRM5 4049/4885KCNH2 41/4885PTGDR2 1691/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.