Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 18/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HK1 | P19367 | 1/20 | 0.45 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | PTGIR | P43119 | 1/20 | 0.44 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.44 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1467495 | 0.92 | PTGDR2 (0.50) | PTGDR2ALDH1A1LMNAMAPTHK1 | |
| SCHEMBL1467687 | 0.91 | PTGDR2 (0.62) | PTGDR2PTGIRPTGDR | |
| SCHEMBL1421903 | 0.89 | PTGDR2 (0.51) | PTGDR2ALDH1A1LMNAMAPTHK1 | |
| SCHEMBL1465473 | 0.88 | PTGDR2 (0.61) | PTGDR2ALDH1A1LMNAMAPTHK1 | |
| SCHEMBL1466489 | 0.87 | PTGDR2 (0.53) | PTGDR2ALDH1A1LMNAMAPTHK1 | |
| SCHEMBL3716596 | 0.86 | PTGDR2 (0.49) | PTGDR2ALDH1A1LMNAMAPTHK1 | |
| SCHEMBL3718517 | 0.84 | PTGDR2 (0.48) | PTGDR2ALDH1A1LMNAMAPTHK1 | |
| SCHEMBL1465741 | 0.83 | PTGDR2 (0.60) | PTGDR2PTGIRPTGDR | |
| SCHEMBL1466355 | 0.82 | PTGDR2 (0.53) | PTGDR2ALDH1A1LMNAMAPTHK1 | |
| SCHEMBL3714601 | 0.82 | PTGDR2 (0.52) | PTGDR2ALDH1A1LMNAMAPTHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2327693-A1 | Indoles and their therapeutic use | Pulmagen Therapeutics (Asthma) Limited (GB) | 2011-06-01 | — | — | EP | disclosed |