Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 19/20 | 0.46 |
| ▸ | PTGDR | Q13258 | 4/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | PTGIR | P43119 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1465372 | 0.85 | PTGDR2 (0.64) | PTGDR2PTGDRPTGIR | |
| SCHEMBL1466783 | 0.84 | PTGDR2 (0.53) | PTGDR2PTGDRPTGIR | |
| SCHEMBL3717849 | 0.76 | PTGDR2 (0.66) | PTGDR2PTGDRPTGIR | |
| SCHEMBL3724054 | 0.75 | PTGDR2 (0.55) | PTGDR2PTGDRPTGIR | |
| SCHEMBL3721648 | 0.75 | PTGDR2 (0.57) | PTGDR2PTGDRPTGIR | |
| SCHEMBL3718517 | 0.73 | PTGDR2 (0.48) | PTGDR2PTGDRPTGIR | |
| SCHEMBL4721932 | 0.72 | PTGDR2 (0.67) | PTGDR2PTGDR | |
| SCHEMBL3719021 | 0.70 | PTGDR2 (0.67) | PTGDR2PTGDRPTGIR | |
| SCHEMBL27699143 | 0.69 | PTGDR2 (0.68) | PTGDR2PTGDRPTGIR | |
| SCHEMBL3721645 | 0.68 | PTGDR2 (0.56) | PTGDR2PTGDRPTGIR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2327693-A1 | Indoles and their therapeutic use | Pulmagen Therapeutics (Asthma) Limited (GB) | 2011-06-01 | — | — | EP | disclosed |
| CN-101970405-A | Indoles and their therapeutic use | PULMAGEN THERAPEUTICS ASTHMA L | 2011-02-09 | — | — | CN | disclosed |
| EP-2229358-A1 | INDOLES AND THEIR THERAPEUTIC USE | Pulmagen Therapeutics (Asthma) Limited (GB) | 2010-09-22 | — | — | EP | disclosed |
| WO-2009077728-A1 | INDOLES AND THEIR THERAPEUTIC USE | ARGENTA DISCOVERY LIMITED (GB) | 2009-06-25 | — | — | WO | disclosed |