Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 2/20 | 1.00 |
| ▸ | PARP1 | P09874 | 5/20 | 0.81 |
| ▸ | PARP10 | Q53GL7 | 5/20 | 0.81 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.59 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.59 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.59 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.59 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.59 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.59 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.59 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.59 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.59 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | PARP14 | Q460N5 | 3/20 | 0.55 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14567079 | 0.94 | KMT2A (0.88) | MEN1KMT2APARP1PARP10HDAC1 | |
| SCHEMBL18671651 | 0.93 | KMT2A (0.87) | MEN1KMT2APARP1PARP10SMN1; SMN2 | |
| SCHEMBL882827 | 0.91 | MEN1 (0.83) | MEN1KMT2APARP1PARP10HDAC1 | |
| SCHEMBL9453278 | 0.91 | MEN1 (0.83) | MEN1KMT2APARP1PARP10HDAC1 | |
| SCHEMBL13370421 | 0.90 | MEN1 (0.81) | MEN1KMT2APARP1PARP10HDAC1 | |
| SCHEMBL26100331 | 0.89 | MEN1 (0.79) | MEN1KMT2APARP1PARP10HDAC1 | |
| SCHEMBL26102702 | 0.88 | MEN1 (0.77) | MEN1KMT2APARP1PARP10HDAC1 | |
| SCHEMBL30493621 | 0.88 | MEN1 (0.77) | MEN1KMT2APARP1PARP10HDAC1 | |
| SCHEMBL3362788 | 0.87 | MEN1 (0.77) | MEN1KMT2APARP1PARP10SMN1; SMN2 | |
| SCHEMBL3646991 | 0.87 | MEN1 (0.76) | MEN1KMT2APARP1PARP10SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020154434-A1 | COMPOSITIONS AND METHODS FOR TREATING AND PREVENTING COGNITIVE DYSFUNCTION | PHARMATROPHIX, INC. (US) | 2020-07-30 | — | — | WO | disclosed |
| EP-2526942-B1 | Methods of facilitating neural cell survival using non-peptide and peptide BDNF neurotrophin mimetics | UNIV NORTH CAROLINA CHAPEL HILL (US) | 2017-08-09 | — | — | EP | disclosed |