Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | XBP1 | P17861 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18462326 | 0.94 | NPSR1 (0.48) | KDM4EMAPTHPGDNPSR1NPC1 | |
| SCHEMBL19627526 | 0.94 | NPSR1 (0.48) | KDM4EMAPTHPGDNPSR1NPC1 | |
| SCHEMBL18462327 | 0.90 | NPSR1 (0.41) | KDM4EMAPTHPGDNPSR1NPC1 | |
| SCHEMBL18418003 | 0.83 | NPSR1 (0.53) | KDM4EMAPTHPGDNPSR1NPC1 | |
| SCHEMBL18417995 | 0.83 | NPSR1 (0.53) | KDM4EMAPTHPGDNPSR1NPC1 | |
| SCHEMBL18418014 | 0.82 | KDM4E (0.48) | KDM4EMAPTHPGDNPSR1NPC1 | |
| SCHEMBL18417999 | 0.81 | KDM4E (0.50) | KDM4EMAPTHPGDNPSR1NPC1 | |
| SCHEMBL18417990 | 0.81 | KDM4E (0.50) | KDM4EMAPTHPGDNPSR1NPC1 | |
| SCHEMBL19625563 | 0.80 | KDM4E (0.44) | KDM4EMAPTHPGDNPSR1NPC1 | |
| SCHEMBL18417998 | 0.79 | NPSR1 (0.46) | KDM4EMAPTHPGDNPSR1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9725473-B2 | Anthracene-9, 10-dione dioxime compound prodrugs and their uses | BETA CAT PHARMACEUTICALS, INC. (US) | 2017-08-08 | — | — | US | disclosed |