Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 10/20 | 0.51 |
| ▸ | PPARG | P37231 | 11/20 | 0.50 |
| ▸ | PPARA | Q07869 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6928284 | 1.00 | FFAR1 (0.51) | FFAR1PPARGPPARA | |
| SCHEMBL14213690 | 0.84 | FFAR1 (0.33) | FFAR1PPARG | |
| SCHEMBL6929740 | 0.83 | PPARG (0.62) | FFAR1PPARGPPARA | |
| SCHEMBL957753 | 0.83 | PPARG (0.62) | FFAR1PPARGPPARA | |
| SCHEMBL6931046 | 0.83 | PPARG (0.62) | FFAR1PPARGPPARA | |
| SCHEMBL19217865 | 0.83 | PPARG (0.62) | FFAR1PPARGPPARA | |
| SCHEMBL6929502 | 0.83 | PPARG (0.62) | FFAR1PPARGPPARA | |
| SCHEMBL6930334 | 0.82 | PPARG (0.52) | FFAR1PPARGPPARA | |
| SCHEMBL19217650 | 0.81 | PPARG (0.56) | FFAR1PPARGPPARA | |
| SCHEMBL6930214 | 0.81 | FFAR1 (0.62) | FFAR1PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3202401-A1 | PPAR-SPARING THIAZOLIDINEDIONES AND COMBINATIONS FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | Octeta Therapeutics, LLC (US) | 2017-08-09 | — | — | EP | disclosed |