Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 11/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.47 |
| ▸ | MPC2 | O95563 | 1/20 | 0.44 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19559787 | 0.91 | PPARG (0.50) | PPARGFFAR1MPC2CYP2C8CYP2C9 | |
| SCHEMBL6928538 | 0.86 | PPARG (0.72) | PPARGFFAR1MPC2CYP2C8CYP2C9 | |
| SCHEMBL6928116 | 0.86 | PPARG (0.72) | PPARGFFAR1MPC2CYP2C8CYP2C9 | |
| SCHEMBL14213631 | 0.83 | PPARG (0.51) | PPARGFFAR1MPC2CYP2C8CYP2C9 | |
| SCHEMBL14213648 | 0.83 | PPARG (0.51) | PPARGFFAR1MPC2CYP2C8CYP2C9 | |
| SCHEMBL19559701 | 0.82 | PPARG (0.51) | PPARGFFAR1MPC2CYP2C8CYP2C9 | |
| SCHEMBL19559731 | 0.77 | PPARG (0.57) | PPARGFFAR1MPC2CYP2C8CYP2C9 | |
| SCHEMBL6930193 | 0.77 | PPARG (0.69) | PPARGFFAR1MPC2CYP2C8CYP2C9 | |
| SCHEMBL15811536 | 0.77 | PPARG (0.69) | PPARGFFAR1MPC2CYP2C8CYP2C9 | |
| SCHEMBL6930317 | 0.77 | PPARG (0.69) | PPARGFFAR1MPC2CYP2C8CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3202401-A1 | PPAR-SPARING THIAZOLIDINEDIONES AND COMBINATIONS FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | Octeta Therapeutics, LLC (US) | 2017-08-09 | — | — | EP | disclosed |