Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 7/20 | 0.78 |
| ▸ | FFAR1 | O14842 | 13/20 | 0.58 |
| ▸ | PPARA | Q07869 | 2/20 | 0.58 |
| ▸ | MPC2 | O95563 | 1/20 | 0.52 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19217796 | 1.00 | PPARG (0.78) | PPARGFFAR1PPARAMPC2CYP2C8 | |
| SCHEMBL6931055 | 0.88 | PPARG (0.76) | PPARGFFAR1PPARAMPC2CYP2C8 | |
| SCHEMBL1360381 | 0.88 | PPARG (0.76) | PPARGFFAR1PPARAMPC2CYP2C8 | |
| SCHEMBL937576 | 0.88 | PPARG (0.76) | PPARGFFAR1PPARAMPC2CYP2C8 | |
| SCHEMBL6929681 | 0.88 | PPARG (0.76) | PPARGFFAR1PPARAMPC2CYP2C8 | |
| SCHEMBL6929663 | 0.88 | PPARG (0.76) | PPARGFFAR1PPARAMPC2CYP2C8 | |
| SCHEMBL6929446 | 0.88 | PPARG (0.76) | PPARGFFAR1PPARAMPC2CYP2C8 | |
| SCHEMBL6929456 | 0.88 | PPARG (0.76) | PPARGFFAR1PPARAMPC2CYP2C8 | |
| SCHEMBL6930080 | 0.88 | PPARG (0.76) | PPARGFFAR1PPARAMPC2CYP2C8 | |
| SCHEMBL6928625 | 0.88 | PPARG (0.75) | PPARGFFAR1PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3202401-A1 | PPAR-SPARING THIAZOLIDINEDIONES AND COMBINATIONS FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | Octeta Therapeutics, LLC (US) | 2017-08-09 | — | — | EP | disclosed |