Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 4/20 | 0.54 |
| ▸ | TSHR | P16473 | 7/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | ESR1 | P03372 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.46 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3885590 | 0.89 | CYP1A2 (0.68) | CYP1A2TSHRL3MBTL1TDP1CYP3A4 | |
| SCHEMBL17449280 | 0.85 | CYP1A2 (0.58) | CYP1A2TSHRL3MBTL1TDP1CYP3A4 | |
| SCHEMBL1095857 | 0.84 | CYP1A2 (0.77) | CYP1A2TSHRL3MBTL1MAPK1ALDH1A1 | |
| SCHEMBL31337797 | 0.84 | CYP1A2 (0.77) | CYP1A2TSHRL3MBTL1MAPK1ALDH1A1 | |
| SCHEMBL12697419 | 0.83 | CYP1A2 (0.60) | CYP1A2TSHRL3MBTL1TDP1CYP3A4 | |
| SCHEMBL28434055 | 0.83 | CYP1A2 (0.64) | CYP1A2TSHRL3MBTL1TDP1CYP3A4 | |
| SCHEMBL30075579 | 0.82 | CYP1A2 (0.54) | CYP1A2TSHRL3MBTL1TDP1CYP3A4 | |
| SCHEMBL8405218 | 0.79 | CYP1A2 (0.72) | CYP1A2TSHRL3MBTL1TDP1CYP3A4 | |
| SCHEMBL8880783 | 0.78 | TSHR (0.47) | CYP1A2TSHRL3MBTL1TDP1CYP3A4 | |
| SCHEMBL7673847 | 0.77 | TSHR (0.50) | CYP1A2TSHRL3MBTL1TDP1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170226106-A1 | CXCR4 Receptor Antagonists | PROXIMAGEN, LLC | 2017-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170226106-A1 | CXCR4 Receptor Antagonists | CXCR4, CXCR1, CXCR2 | CYP1A2 1917/4885TSHR 233/4885L3MBTL1 2675/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.