SCHEMBL1922492

SCHEMBL1922492

CNCCCCCCCCCN1CCC(OC(=O)Nc2ccccc2-c2ccccc2)CC1

nearest known ligand 0.81

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CHRM3 P20309 20/20 0.81

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL1922490 0.99 CHRM3 (0.80) CHRM3
SCHEMBL13590462 0.93 CHRM3 (0.90) CHRM3
SCHEMBL13590186 0.93 CHRM3 (0.90) CHRM3
SCHEMBL13590343 0.93 CHRM3 (0.90) CHRM3
SCHEMBL13590261 0.93 CHRM3 (0.90) CHRM3
SCHEMBL13590412 0.93 CHRM3 (0.90) CHRM3
SCHEMBL13590176 0.93 CHRM3 (0.90) CHRM3
SCHEMBL13590397 0.93 CHRM3 (0.90) CHRM3
SCHEMBL266147 0.92 CHRM3 (0.80) CHRM3
SCHEMBL13590162 0.92 CHRM3 (0.89) CHRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011083387-A1 HYDROCHLORIDE SALT OF BIPHENYL-2-YL-CARBAMIC ACID 1-{9-[(3-FLUORO-4-HYDROXY-BENZOYL)-METHYL-AMINO]-NONYL}-PIPERIDIN-4-YL ESTER PFIZER LIMITED (GB) 2011-07-14 WO disclosed
WO-2011083387-A1 HYDROCHLORIDE SALT OF BIPHENYL-2-YL-CARBAMIC ACID 1-{9-[(3-FLUORO-4-HYDROXY-BENZOYL)-METHYL-AMINO]-NONYL}-PIPERIDIN-4-YL ESTER PFIZER LIMITED (GB) 2011-07-14 WO disclosed
EP-2328868-A1 NOVEL COMPOUNDS ACTIVE AS MUSCARINIC RECEPTOR ANTAGONISTS Pfizer Limited (GB) 2011-06-08 EP disclosed
WO-2010007552-A1 NOVEL COMPOUNDS ACTIVE AS MUSCARINIC RECEPTOR ANTAGONISTS PFIZER LIMITED (GB) 2010-01-21 WO disclosed
WO-2010007552-A1 NOVEL COMPOUNDS ACTIVE AS MUSCARINIC RECEPTOR ANTAGONISTS PFIZER LIMITED (GB) 2010-01-21 WO disclosed
US-20100016366-A1 Novel Compounds Active as Muscarinic Receptor Antagonists GLOSSOP PAUL ALAN 2010-01-21 US disclosed
US-20100016366-A1 Novel Compounds Active as Muscarinic Receptor Antagonists GLOSSOP PAUL ALAN 2010-01-21 US disclosed
US-20100016366-A1 Novel Compounds Active as Muscarinic Receptor Antagonists GLOSSOP PAUL ALAN 2010-01-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100016366-A1 Novel Compounds Active as Muscarinic Receptor Antagonists CHRM3, CHRM2, CHRM5 CHRM3 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.