SCHEMBL19225490

SCHEMBL19225490

CC(Oc1cc(C(=O)O)ncc1C1CC1)C(F)(F)F

nearest known ligand 0.65

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 20/20 0.65
CNR1 P21554 2/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15777540 1.00 CNR2 (0.65) CNR2CNR1
SCHEMBL15777535 1.00 CNR2 (0.65) CNR2CNR1
SCHEMBL15776636 0.95 CNR2 (0.60) CNR2CNR1
SCHEMBL28025786 0.95 CNR2 (0.60) CNR2CNR1
SCHEMBL15776142 0.82 CNR2 (0.83) CNR2CNR1
SCHEMBL15776819 0.82 CNR2 (0.60) CNR2CNR1
SCHEMBL16115494 0.81 CNR2 (0.61) CNR2
SCHEMBL16115492 0.81 CNR2 (0.61) CNR2
SCHEMBL16115493 0.81 CNR2 (0.61) CNR2
SCHEMBL19223695 0.81 CNR2 (0.59) CNR2CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104837818-A Pyridine-2-amides useful as CB2 agonists HOFFMANN LA ROCHE 2015-08-12 CN claimed
EP-2928867-B1 PYRIDINE-2-AMIDES USEFUL AS CB2 AGONISTS HOFFMANN LA ROCHE (CH) 2017-08-09 EP disclosed
CN-104837818-A Pyridine-2-amides useful as CB2 agonists HOFFMANN LA ROCHE 2015-08-12 CN disclosed