SCHEMBL19225636

SCHEMBL19225636

CC/C(O)=C(/N)C(C)(NC(=O)c1cc(OCC(F)(F)F)c(Br)cn1)C1CC1

nearest known ligand 0.52

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 20/20 0.52
CNR1 P21554 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15790090 0.89 CNR2 (0.51) CNR2CNR1
SCHEMBL17308852 0.85 CNR2 (0.54) CNR2CNR1
SCHEMBL19225453 0.83 CNR2 (0.58) CNR2CNR1
SCHEMBL19225639 0.83 CNR2 (0.49) CNR2CNR1
SCHEMBL15790183 0.83 CNR2 (0.49) CNR2CNR1
SCHEMBL19225638 0.80 CNR2 (0.46) CNR2CNR1
SCHEMBL17308776 0.78 CNR2 (0.54) CNR2CNR1
SCHEMBL19225554 0.76 CNR2 (0.67) CNR2CNR1
SCHEMBL19225538 0.73 CNR2 (0.51) CNR2CNR1
SCHEMBL19225539 0.73 CNR2 (0.52) CNR2CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2928867-B1 PYRIDINE-2-AMIDES USEFUL AS CB2 AGONISTS HOFFMANN LA ROCHE (CH) 2017-08-09 EP disclosed