Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL104620 | 0.90 | USP2 (0.47) | USP2SMN1; SMN2HTTALDH1A1CHRM2 | |
| SCHEMBL19230079 | 0.88 | USP2 (0.45) | USP2SMN1; SMN2HTTALDH1A1CHRM2 | |
| SCHEMBL1906525 | 0.86 | USP2 (0.44) | USP2SMN1; SMN2HTTALDH1A1CHRM2 | |
| SCHEMBL8242595 | 0.86 | USP2 (0.61) | USP2SMN1; SMN2HTTALDH1A1CHRM2 | |
| SCHEMBL20232006 | 0.85 | USP2 (0.49) | USP2SMN1; SMN2HTTALDH1A1CHRM2 | |
| SCHEMBL16825817 | 0.85 | USP2 (0.49) | USP2SMN1; SMN2HTTALDH1A1CHRM2 | |
| SCHEMBL22060030 | 0.84 | USP2 (0.45) | USP2SMN1; SMN2HTTALDH1A1CHRM2 | |
| SCHEMBL13600638 | 0.83 | USP2 (0.44) | USP2SMN1; SMN2HTTALDH1A1CHRM2 | |
| SCHEMBL20873847 | 0.83 | USP2 (0.53) | USP2SMN1; SMN2CHRM2CHRM4CHRM1 | |
| SCHEMBL19230247 | 0.83 | USP2 (0.41) | USP2SMN1; SMN2HTTALDH1A1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017136769-A1 | PEPTIDE DRUG CONJUGATES | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2017-08-10 | — | — | WO | disclosed |