Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | PREP | P48147 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17081077 | 0.80 | NR1H2 (0.44) | NR1H2USP2SMN1; SMN2GPR119NAMPT | |
| SCHEMBL136365 | 0.79 | NR1H2 (0.43) | NR1H2USP2SMN1; SMN2GPR119NAMPT | |
| SCHEMBL28296118 | 0.79 | NR1H2 (0.43) | NR1H2USP2SMN1; SMN2GPR119NAMPT | |
| SCHEMBL22468373 | 0.79 | NR1H2 (0.43) | NR1H2USP2SMN1; SMN2GPR119NAMPT | |
| SCHEMBL13801225 | 0.79 | USP2 (0.50) | NR1H2USP2SMN1; SMN2GPR119HPGD | |
| SCHEMBL16356224 | 0.75 | NR1H2 (0.43) | NR1H2USP2SMN1; SMN2GPR119NAMPT | |
| SCHEMBL16366769 | 0.75 | NR1H2 (0.43) | NR1H2USP2SMN1; SMN2GPR119NAMPT | |
| SCHEMBL4697255 | 0.74 | NR1H2 (0.39) | NR1H2USP2SMN1; SMN2GPR119CHRM2 | |
| SCHEMBL4697250 | 0.74 | NR1H2 (0.39) | NR1H2USP2SMN1; SMN2GPR119CHRM2 | |
| SCHEMBL4697252 | 0.74 | NR1H2 (0.39) | NR1H2USP2SMN1; SMN2GPR119CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017134588-A1 | PROCESS FOR THE PREPARATION OF IBRUTINIB | SHILPA MEDICARE LIMITED (IN) | 2017-08-10 | — | — | WO | disclosed |