Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 20/20 | 0.56 |
| ▸ | FXR2 | P51116 | 1/20 | 0.54 |
| ▸ | FABP1 | P07148 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19230519 | 0.87 | NR1H4 (0.64) | NR1H4FXR2FABP1 | |
| SCHEMBL19230674 | 0.87 | NR1H4 (0.57) | NR1H4FXR2FABP1 | |
| SCHEMBL28835403 | 0.82 | NR1H4 (0.64) | NR1H4FXR2FABP1 | |
| SCHEMBL29904882 | 0.82 | NR1H4 (0.64) | NR1H4FXR2FABP1 | |
| SCHEMBL19230542 | 0.82 | NR1H4 (0.58) | NR1H4FXR2FABP1 | |
| SCHEMBL19230765 | 0.81 | NR1H4 (0.56) | NR1H4FXR2FABP1 | |
| SCHEMBL19230538 | 0.81 | NR1H4 (0.54) | NR1H4FXR2FABP1 | |
| SCHEMBL19230515 | 0.80 | NR1H4 (0.74) | NR1H4FXR2 | |
| SCHEMBL19230521 | 0.80 | NR1H4 (0.74) | NR1H4FXR2 | |
| SCHEMBL19230541 | 0.80 | NR1H4 (0.74) | NR1H4FXR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017133521-A1 | FXR RECEPTOR AGONIST | 山东轩竹医药科技有限公司 | 2017-08-10 | — | — | WO | disclosed |