Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 2/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.41 |
| ▸ | SCD | O00767 | 7/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GBA1 | P04062 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1781671 | 0.94 | SCD (0.42) | HCRTR1HCRTR2SCDTP53HTT | |
| SCHEMBL1781823 | 0.94 | HCRTR1 (0.45) | HCRTR1HCRTR2SCDTP53HTT | |
| SCHEMBL1782074 | 0.84 | SCD (0.47) | SCDGBA1 | |
| SCHEMBL1779608 | 0.84 | SCD (0.52) | SCDGBA1 | |
| SCHEMBL1780680 | 0.81 | HCRTR1 (0.47) | HCRTR1HCRTR2SCDTP53HTT | |
| SCHEMBL1781570 | 0.76 | SCD (0.51) | SCDGBA1 | |
| SCHEMBL1781966 | 0.75 | SCD (0.54) | SCDGBA1 | |
| SCHEMBL1780586 | 0.74 | HCRTR1 (0.47) | HCRTR1HCRTR2SCDTP53HTT | |
| SCHEMBL1780313 | 0.73 | HTT (0.51) | HCRTR1HCRTR2SCDHTTKMT2A | |
| SCHEMBL1781932 | 0.73 | DRD4 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2328886-A1 | DERIVATIVES OF TRIAZINES AND URACILS, THEIR PREPARATION AND THEIR APPLICATION IN HUMAN THERAPEUTICS | Pierre Fabre Médicament (FR) | 2011-06-08 | — | — | EP | disclosed |
| WO-2010006962-A1 | DERIVATIVES OF TRIAZINES AND URACILS, THEIR PREPARATION AND THEIR APPLICATION IN HUMAN THERAPEUTICS | PIERRE FABRE MEDICAMENT (FR) | 2010-01-21 | — | — | WO | disclosed |