Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20725644 | 0.89 | BRAF (0.56) | BRAFKDR | |
| SCHEMBL14964588 | 0.87 | BRAF (0.77) | BRAF | |
| SCHEMBL20577794 | 0.86 | BRAF (0.57) | BRAFKDR | |
| SCHEMBL15304986 | 0.86 | KDR (0.64) | BRAFKDR | |
| SCHEMBL19233398 | 0.86 | PIK3CA (0.46) | BRAFKDR | |
| SCHEMBL9912806 | 0.86 | BRAF (0.52) | BRAFKDR | |
| SCHEMBL14964675 | 0.86 | BRAF (0.69) | BRAF | |
| SCHEMBL20725632 | 0.85 | BRAF (0.55) | BRAFKDR | |
| SCHEMBL19233241 | 0.85 | KDR (0.78) | BRAFKDR | |
| SCHEMBL9912802 | 0.85 | BRAF (0.78) | BRAFKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017135589-A9 | PYRIDINE DERIVATIVE INHIBITING RAF KINASE AND VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR, METHOD FOR PREPARING SAME, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND USE THEREOF | 삼진제약주식회사 | 2017-10-19 | — | — | WO | disclosed |
| WO-2017135589-A1 | PYRIDINE DERIVATIVE INHIBITING RAF KINASE AND VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR, METHOD FOR PREPARING SAME, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND USE THEREOF | 삼진제약주식회사 | 2017-08-10 | — | — | WO | disclosed |