Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 20/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19233325 | 0.89 | KDR (0.63) | KDR | |
| SCHEMBL29448738 | 0.89 | KDR (0.63) | KDR | |
| SCHEMBL29448688 | 0.85 | KDR (0.65) | KDR | |
| SCHEMBL19233231 | 0.85 | KDR (0.65) | KDR | |
| SCHEMBL19233202 | 0.85 | KDR (0.51) | KDR | |
| SCHEMBL19233403 | 0.84 | KDR (0.80) | KDR | |
| SCHEMBL29448695 | 0.84 | KDR (0.80) | KDR | |
| SCHEMBL19233323 | 0.83 | KDR (0.62) | KDR | |
| SCHEMBL19233234 | 0.83 | KDR (0.62) | KDR | |
| SCHEMBL29448718 | 0.83 | KDR (0.62) | KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017135589-A9 | PYRIDINE DERIVATIVE INHIBITING RAF KINASE AND VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR, METHOD FOR PREPARING SAME, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND USE THEREOF | 삼진제약주식회사 | 2017-10-19 | — | — | WO | disclosed |
| WO-2017135589-A1 | PYRIDINE DERIVATIVE INHIBITING RAF KINASE AND VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR, METHOD FOR PREPARING SAME, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND USE THEREOF | 삼진제약주식회사 | 2017-08-10 | — | — | WO | disclosed |