Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 13/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.38 |
| ▸ | RBP4 | P02753 | 1/20 | 0.34 |
| ▸ | TTR | P02766 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1780694 | 0.83 | SCD (0.54) | SCD | |
| SCHEMBL1781541 | 0.82 | SCD (0.59) | SCDRBP4TTR | |
| SCHEMBL1782523 | 0.76 | SCD (0.55) | SCDADRA1DADRA1AADRA1B | |
| SCHEMBL1780668 | 0.76 | SCD (0.65) | SCDRBP4TTR | |
| SCHEMBL1781074 | 0.74 | SCD (0.59) | SCDRBP4TTR | |
| SCHEMBL1781011 | 0.73 | SCD (0.59) | SCDRBP4TTRCYP3A4 | |
| SCHEMBL1783078 | 0.71 | SCD (0.51) | SCDRBP4TTRCYP3A4 | |
| SCHEMBL1779895 | 0.70 | SCD (0.67) | SCDRBP4TTR | |
| SCHEMBL1779604 | 0.70 | SCD (0.60) | SCDRBP4TTR | |
| SCHEMBL1782516 | 0.70 | SCD (0.58) | SCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2011528007-A | — | — | 2011-11-10 | — | — | JP | claimed |
| EP-2328886-A1 | DERIVATIVES OF TRIAZINES AND URACILS, THEIR PREPARATION AND THEIR APPLICATION IN HUMAN THERAPEUTICS | Pierre Fabre Médicament (FR) | 2011-06-08 | — | — | EP | claimed |
| WO-2010006962-A1 | DERIVATIVES OF TRIAZINES AND URACILS, THEIR PREPARATION AND THEIR APPLICATION IN HUMAN THERAPEUTICS | PIERRE FABRE MEDICAMENT (FR) | 2010-01-21 | — | — | WO | claimed |