SCHEMBL192382

SCHEMBL192382

[NH]C(N)=S

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Thiourea SCHEMBL30536978 0.72
Thiourea SCHEMBL30536984 0.72
Thiourea SCHEMBL1008 0.72
SCHEMBL4877351 0.72
Thiourea SCHEMBL850383 0.72
Guanidine SCHEMBL2461124 0.71
Thiourea SCHEMBL8657126 0.67
Guanidine SCHEMBL6274766 0.67 TSHR (0.46)
Guanidine SCHEMBL6271074 0.67
Thiourea SCHEMBL5590390 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2643 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4399527-A1 A METHOD OF DETERMINING THE PRESENCE OF AN ANALYTE IN A SAMPLE Valitacell Limited (IE) 2024-07-17 EP claimed
US-20240228785-A1 Fluorogenic pH-Sensitive Compounds and Their Methods of Use Life Technologies Corporation 2024-07-11 US claimed
US-20240189333-A1 PHOSPHOLIPID COMPOUNDS AND FORMULATIONS APPLAUD MEDICAL, INC. 2024-06-13 US claimed
CN-117999483-A Method for determining the presence of an analyte in a sample 瓦里泰细胞有限公司 2024-05-07 CN claimed
US-20240067600-A1 SMALL MOLECULE INHIBITORS OF THE MITOCHONDRIAL PERMEABILITY TRANSITION PORE (mtPTP) UNIVERSITY OF KANSAS (US) 2024-02-29 US claimed
US-11867698-B2 Fluorogenic pH sensitive dyes and their method of use Life Technologies Corporation (US) 2024-01-09 US claimed
WO-2023147571-A2 SELECTIVE AGENTS TARGETING MYCOBACTERIUM TUBERCULOSIS UNIVERSITY OF MISSISSIPPI (US) 2023-08-03 WO claimed
US-11667611-B2 Compositions and methods for inhibition of the JAK pathway RIGEL PHARMACEUTICALS, INC. (US) 2023-06-06 US claimed
WO-2023036965-A1 A METHOD OF DETERMINING THE PRESENCE OF AN ANALYTE IN A SAMPLE. VALITACELL LIMITED (IE) 2023-03-16 WO claimed
US-11554094-B2 Synthesis and application of microbubble-forming compounds CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2023-01-17 US claimed
US-5108747-A STABLE OXPENEM-3-CARBOXYLIC ACIDS AS BETA-LACTAMASE INHIBITORS BAYER AKTIENGESELLSCHAFT (DE) 1992-04-28 US claimed
US-5096899-A Nonhydrolyzing oxapenicillins BAYER AKTIENGESELLSCHAFT (DE) 1992-03-17 US claimed
EP-0362622-A1 Use of stable oxapenem-3-carboxylic acids for the manufacture of beta-lactamase inhibiting medicaments ELI LILLY AND COMPANY (US) 1990-04-11 EP claimed
US-4847251-A CARDIOVASCULAR DISORDERS BOEHRINGER MANNHEIM GMBH (DE) 1989-07-11 US claimed
EP-0301394-A1 Stable oxapenem-3-carboxylic acids Pfaendler, Hans Rudolf, Prof. Dr. (DE) 1989-02-01 EP claimed
EP-0255704-A2 Pyridazinone derivatives, process for their preparation and their use as medicines Roche Diagnostics GmbH (DE) 1988-02-10 EP claimed
US-4590192-A ANTIULCER AGENTS BEECHAM GROUP P.L.C. (GB) 1986-05-20 US claimed
US-4560765-A USING 183-THIAZOL-4-YL GLYOXYLIC ACID AS INTERMEDIATE FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1985-12-24 US claimed
US-4558044-A ANTISECRETORY AGENTS BEECHAM GROUP P.L.C. (GB) 1985-12-10 US claimed
EP-0105732-A2 Histamine H2 receptor antagonists of the benzisothiazole amino and benzthiadiazine amino series BEECHAM GROUP PLC (GB) 1984-04-18 EP claimed