SCHEMBL19244306

SCHEMBL19244306

CCCOC(=O)C=Cc1cccc(OCCC)c1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 6/20 0.60
KDM4E B2RXH2 3/20 0.58
ALDH1A1 P00352 2/20 0.58
SMN1; SMN2 Q16637 1/20 0.58
ALOX5 P09917 1/20 0.52
KMT2A Q03164 1/20 0.51
TLR4 O00206 2/20 0.51
TLR2 O60603 2/20 0.51
CA12 O43570 1/20 0.51
CA1 P00915 1/20 0.51
CA4 P22748 1/20 0.51
CA6 P23280 1/20 0.51
CA5A P35218 1/20 0.51
CA7 P43166 1/20 0.51
CA9 Q16790 1/20 0.51
CA14 Q9ULX7 1/20 0.51
CA5B Q9Y2D0 1/20 0.51
AKR1B10 O60218 2/20 0.50
AKR1B1 P15121 2/20 0.50
PKM P14618 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19244236 0.95 APP (0.59) APPKDM4EALDH1A1SMN1; SMN2ALOX5
SCHEMBL19244298 0.93 APP (0.61) APPKDM4EALDH1A1SMN1; SMN2KMT2A
SCHEMBL19244204 0.93 KDM4E (0.68) APPKDM4EALDH1A1SMN1; SMN2ALOX5
SCHEMBL7222278 0.93 KDM4E (0.60) APPKDM4EALDH1A1SMN1; SMN2ALOX5
SCHEMBL19244203 0.93 KDM4E (0.68) APPKDM4EALDH1A1SMN1; SMN2ALOX5
SCHEMBL7222274 0.93 KDM4E (0.60) APPKDM4EALDH1A1SMN1; SMN2ALOX5
SCHEMBL19244390 0.90 APP (0.64) APPKDM4EALDH1A1SMN1; SMN2TLR4
SCHEMBL15026294 0.90 APP (0.64) APPKDM4EALDH1A1SMN1; SMN2TLR4
SCHEMBL19244235 0.89 KDM4E (0.58) APPKDM4EALDH1A1SMN1; SMN2KMT2A
SCHEMBL19244191 0.89 APP (0.60) APPKDM4EALDH1A1ALOX5KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3208301-B1 RESIN COMPOSITION AND OPTICAL COMPENSATION FILM USING SAME TOSOH CORP (JP) 2019-04-03 EP disclosed
US-10126478-B2 Resin composition and optical compensation film using same TOSOH CORPORATION (JP) 2018-11-13 US disclosed
US-20170242174-A1 RESIN COMPOSITION AND OPTICAL COMPENSATION FILM USING SAME TOSOH CORPORATION (JP) 2017-08-24 US disclosed
EP-3208301-A1 RESIN COMPOSITION AND OPTICAL COMPENSATION FILM USING SAME Tosoh Corporation (JP) 2017-08-23 EP disclosed