Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 15/20 | 0.47 |
| ▸ | CARM1 | Q86X55 | 10/20 | 0.47 |
| ▸ | KDM1A | O60341 | 2/20 | 0.43 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.37 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.37 |
| ▸ | MOK | Q9UQ07 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19432195 | 0.92 | PRMT1 (0.44) | PRMT1CARM1KDM1A | |
| SCHEMBL16204172 | 0.88 | PRMT1 (0.43) | PRMT1CARM1PRMT6PRMT8MOK | |
| SCHEMBL16194531 | 0.88 | PRMT1 (0.43) | PRMT1CARM1PRMT6PRMT8 | |
| SCHEMBL16204220 | 0.87 | PRMT1 (0.58) | PRMT1CARM1PRMT6PRMT8 | |
| Hydrochloric Acid SCHEMBL16194503 | 0.87 | PRMT1 (0.45) | PRMT1CARM1 | |
| SCHEMBL16204193 | 0.86 | PRMT1 (0.53) | PRMT1CARM1PRMT6PRMT8 | |
| SCHEMBL16204225 | 0.86 | PRMT1 (0.44) | PRMT1CARM1PRMT6PRMT8MOK | |
| SCHEMBL17758367 | 0.85 | PRMT1 (0.45) | PRMT1CARM1PRMT6PRMT8 | |
| SCHEMBL19432035 | 0.85 | KDM1A (0.49) | PRMT1CARM1KDM1APRMT6PRMT8 | |
| SCHEMBL16204272 | 0.85 | PRMT1 (0.43) | PRMT1CARM1PRMT6PRMT8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017136699-A1 | ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF | EPIZYME, INC (US) | 2017-08-10 | — | — | WO | disclosed |