Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GUSB | P08236 | 2/20 | 0.38 |
| ▸ | GBA1 | P04062 | 1/20 | 0.36 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.33 |
| ▸ | FDPS | P14324 | 1/20 | 0.33 |
| ▸ | GLB1 | P16278 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19661491 | 0.90 | — | — | |
| SCHEMBL21250677 | 0.81 | — | — | |
| SCHEMBL19245802 | 0.77 | GLB1 (0.34) | GUSBGBA1GLB1 | |
| SCHEMBL19661534 | 0.77 | SPHK1 (0.39) | GUSBSPHK1 | |
| SCHEMBL19661508 | 0.77 | SPHK1 (0.39) | GUSBSPHK1 | |
| SCHEMBL10119954 | 0.75 | MAP3K12 (0.31) | — | |
| SCHEMBL19135667 | 0.75 | SPHK1 (0.36) | SPHK1 | |
| SCHEMBL26066305 | 0.75 | GLB1 (0.32) | GUSBGBA1GLB1 | |
| SCHEMBL19135669 | 0.74 | KMT2A (0.37) | SPHK1 | |
| SCHEMBL19661527 | 0.74 | KMT2A (0.37) | SPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9730939-B2 | Heterocyclylamines as PI3K inhibitors | INCYTE HOLDINGS CORPORATION (US) | 2017-08-15 | — | — | US | disclosed |