Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PDE4A | P27815 | 4/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.42 |
| ▸ | PDE5A | O76074 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 5/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17682196 | 0.90 | KMT2A (0.46) | KMT2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL17682132 | 0.87 | KMT2A (0.44) | KMT2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL17682199 | 0.87 | KMT2A (0.44) | KMT2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL17682200 | 0.87 | KMT2A (0.44) | KMT2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL17682149 | 0.85 | KMT2A (0.45) | KMT2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL17682207 | 0.85 | KMT2A (0.45) | KMT2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL17682203 | 0.85 | KMT2A (0.45) | KMT2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL17682208 | 0.84 | KMT2A (0.46) | KMT2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL17682279 | 0.80 | KMT2A (0.48) | KMT2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL17682249 | 0.80 | KMT2A (0.48) | KMT2APDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3205652-A1 | HYDROXYL PURINE COMPOUNDS AND APPLICATIONS THEREOF | Medshine Discovery Inc. (CN) | 2017-08-16 | — | — | EP | disclosed |