Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR5 | P35346 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.41 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1748419 | 0.92 | SSTR5 (0.50) | SSTR5ALDH1A1SIGMAR1CXCR3MCHR1 | |
| SCHEMBL1748534 | 0.87 | SSTR5 (0.56) | SSTR5ALDH1A1SIGMAR1CXCR3MCHR1 | |
| SCHEMBL28776967 | 0.87 | SSTR5 (0.49) | SSTR5ALDH1A1SIGMAR1CXCR3SSTR1 | |
| SCHEMBL1748681 | 0.87 | SSTR5 (0.45) | SSTR5ALDH1A1SIGMAR1CXCR3MCHR1 | |
| SCHEMBL1748820 | 0.85 | SSTR5 (0.55) | SSTR5ALDH1A1SIGMAR1CXCR3MCHR1 | |
| SCHEMBL28776964 | 0.85 | SSTR5 (0.49) | SSTR5ALDH1A1SIGMAR1CXCR3SSTR1 | |
| SCHEMBL1748412 | 0.83 | SSTR5 (0.50) | SSTR5ALDH1A1CXCR3MCHR1 | |
| SCHEMBL28944529 | 0.82 | SSTR5 (0.45) | SSTR5ALDH1A1SIGMAR1CXCR3SSTR1 | |
| SCHEMBL28944528 | 0.81 | SSTR5 (0.45) | SSTR5ALDH1A1SIGMAR1CXCR3SSTR1 | |
| SCHEMBL1748228 | 0.81 | SSTR5 (0.56) | SSTR5CXCR3FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2044054-B1 | PYRIMIDINE AND QUINAZOLINE DERIVATIVES AS MODULATORS OF SOMATOSTATINE RECEPTOR ACTIVITY | HOFFMANN LA ROCHE (CH) | 2011-06-08 | — | — | EP | disclosed |