Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.55 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.48 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.48 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD5 | P21918 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23600074 | 1.00 | HRH3 (0.55) | HRH3CARM1PRMT6PRMT8ALDH1A1 | |
| SCHEMBL81143 | 1.00 | — | — | |
| SCHEMBL1685364 | 1.00 | HRH3 (0.55) | HRH3CARM1PRMT6PRMT8ALDH1A1 | |
| SCHEMBL14926143 | 1.00 | HRH3 (0.55) | HRH3CARM1PRMT6PRMT8ALDH1A1 | |
| SCHEMBL2745438 | 1.00 | — | — | |
| Fluoride SCHEMBL1963693 | 0.97 | HRH3 (0.52) | HRH3CARM1PRMT6PRMT8ALDH1A1 | |
| Iodide SCHEMBL8060471 | 0.97 | HRH3 (0.52) | HRH3CARM1PRMT6PRMT8ALDH1A1 | |
| Bromide SCHEMBL1961470 | 0.97 | HRH3 (0.52) | HRH3CARM1PRMT6PRMT8ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7022010 | 0.97 | HRH3 (0.52) | HRH3CARM1PRMT6PRMT8ALDH1A1 | |
| Methane SCHEMBL28014910 | 0.97 | HRH3 (0.52) | HRH3CARM1PRMT6PRMT8ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017136403-A1 | HEPATITIS B ANTIVIRAL AGENTS | ENANTA PHARMACEUTICALS, INC. (US) | 2017-08-10 | — | — | WO | disclosed |