Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.39 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19678151 | 0.84 | KDM1A (0.43) | PARP1SMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL19417372 | 0.78 | SMN1; SMN2 (0.41) | PARP1SMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL24711679 | 0.76 | PARP1 (0.48) | PARP1SMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL19678165 | 0.75 | SMN1; SMN2 (0.46) | SMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL29085641 | 0.73 | PARP1 (0.53) | PARP1SMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL28425343 | 0.73 | PARP1 (0.53) | PARP1SMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL3443702 | 0.70 | KDM1A (0.50) | PARP1POLBKMT2AMAPTALDH1A1 | |
| SCHEMBL10229452 | 0.70 | KDM1A (0.50) | PARP1POLBKMT2AMAPTALDH1A1 | |
| SCHEMBL6546795 | 0.69 | TP53 (0.47) | PARP1SMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL11787753 | 0.69 | PARP1 (0.52) | PARP1SMN1; SMN2POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017136403-A1 | HEPATITIS B ANTIVIRAL AGENTS | ENANTA PHARMACEUTICALS, INC. (US) | 2017-08-10 | — | — | WO | disclosed |