Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22752310 | 1.00 | CNR2 (0.45) | CNR2CNR1 | |
| SCHEMBL19139344 | 0.93 | CNR2 (0.38) | CNR2CNR1 | |
| SCHEMBL19251066 | 0.86 | HCAR2 (0.32) | CNR2CNR1 | |
| SCHEMBL19176941 | 0.84 | CNR2 (0.35) | CNR2CNR1 | |
| SCHEMBL20869384 | 0.82 | CNR2 (0.53) | CNR2CNR1 | |
| SCHEMBL22752547 | 0.81 | CNR2 (0.45) | CNR2CNR1 | |
| SCHEMBL19251551 | 0.79 | HCAR2 (0.34) | — | |
| SCHEMBL20927117 | 0.78 | CNR2 (0.47) | CNR2CNR1 | |
| SCHEMBL22752359 | 0.77 | TLR8 (0.35) | — | |
| SCHEMBL22752346 | 0.76 | HCAR2 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9732083-B2 | Tricyclic gyrase inhibitors | MERCK SHARP & DOHME CORP. (US) | 2017-08-15 | — | — | US | disclosed |