Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 9/20 | 0.38 |
| ▸ | CNR1 | P21554 | 8/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19251056 | 1.00 | CNR2 (0.38) | CNR2CNR1CYP19A1TDP1L3MBTL1 | |
| SCHEMBL18935500 | 1.00 | CNR2 (0.38) | CNR2CNR1CYP19A1TDP1L3MBTL1 | |
| SCHEMBL19251174 | 1.00 | CNR2 (0.38) | CNR2CNR1CYP19A1TDP1L3MBTL1 | |
| SCHEMBL18852713 | 0.98 | CNR2 (0.37) | CNR2CNR1CYP19A1TDP1L3MBTL1 | |
| SCHEMBL18721019 | 0.98 | CNR2 (0.37) | CNR2CNR1CYP19A1TDP1L3MBTL1 | |
| SCHEMBL22007446 | 0.98 | CYP19A1 (0.37) | CNR2CNR1CYP19A1TDP1L3MBTL1 | |
| SCHEMBL19251062 | 0.96 | CNR2 (0.36) | CNR2CNR1CYP19A1 | |
| SCHEMBL18909511 | 0.96 | CYP19A1 (0.36) | CNR2CNR1CYP19A1TDP1L3MBTL1 | |
| SCHEMBL19135597 | 0.93 | CYP19A1 (0.38) | CNR2CNR1CYP19A1 | |
| SCHEMBL18382253 | 0.92 | CYP19A1 (0.38) | CNR2CNR1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9732083-B2 | Tricyclic gyrase inhibitors | MERCK SHARP & DOHME CORP. (US) | 2017-08-15 | — | — | US | disclosed |