Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 7/20 | 0.33 |
| ▸ | PIK3R1 | P27986 | 7/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29109311 | 1.00 | PIK3CD (0.33) | PIK3CDPIK3R1KDM4C | |
| SCHEMBL29109355 | 0.90 | PIK3CD (0.33) | PIK3CDPIK3R1 | |
| SCHEMBL29109354 | 0.90 | PIK3CD (0.33) | PIK3CDPIK3R1 | |
| SCHEMBL29109336 | 0.84 | — | — | |
| SCHEMBL29109337 | 0.84 | — | — | |
| SCHEMBL19251618 | 0.82 | GAA (0.41) | PIK3CDPIK3R1 | |
| SCHEMBL30604511 | 0.75 | PIK3CD (0.31) | PIK3CDPIK3R1 | |
| SCHEMBL29109283 | 0.75 | PIK3CD (0.31) | PIK3CDPIK3R1 | |
| SCHEMBL29109282 | 0.75 | PIK3CD (0.31) | PIK3CDPIK3R1 | |
| SCHEMBL30604520 | 0.75 | PIK3CD (0.37) | PIK3CDPIK3R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117088867-A | Inhalable aromatic ring thiazide and analogue, pharmaceutical composition containing inhalable aromatic ring thiazide and analogue and application of inhalable aromatic ring thiazide and analogue in anti-inflammatory and anti-tumor | 杭州百诚医药科技股份有限公司 | 2023-11-21 | — | — | CN | disclosed |
| WO-2017133655-A1 | BENZOTHIAZINE AND BENZOTHIADIAZINE COMPOUNDS AND PREPARATION AND USE | 浙江大学 | 2017-08-10 | — | — | WO | disclosed |