Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 18/20 | 0.78 |
| ▸ | PIK3R1 | P27986 | 17/20 | 0.78 |
| ▸ | PIK3CG | P48736 | 8/20 | 0.44 |
| ▸ | PIK3CB | P42338 | 7/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.44 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | PRKDC | P78527 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19251422 | 0.90 | PIK3CD (0.70) | PIK3CDPIK3R1PIK3CGPIK3CBPIK3CA | |
| SCHEMBL19251406 | 0.81 | PIK3CD (0.53) | PIK3CDPIK3R1PIK3CGPIK3CBPIK3CA | |
| SCHEMBL19251420 | 0.77 | PIK3R1 (0.76) | PIK3CDPIK3R1PIK3CGPIK3CBPIK3CA | |
| SCHEMBL19251407 | 0.76 | PIK3CD (1.00) | PIK3CDPIK3R1PIK3CGPIK3CBPIK3CA | |
| SCHEMBL19251630 | 0.74 | PIK3R1 (0.61) | PIK3CDPIK3R1PIK3CGPIK3CBPIK3CA | |
| SCHEMBL19251386 | 0.71 | PIK3CD (0.47) | PIK3CDPIK3R1PIK3CGPIK3CBPIK3CA | |
| SCHEMBL19251423 | 0.70 | PIK3CD (0.50) | PIK3CDPIK3R1PIK3CGPIK3CBPIK3CA | |
| SCHEMBL16568154 | 0.69 | PIK3CD (0.47) | PIK3CDPIK3R1PIK3CGPIK3CBPIK3CA | |
| SCHEMBL19072474 | 0.69 | PIK3CD (0.45) | PIK3CDPIK3R1PIK3CGPIK3CBPIK3CA | |
| SCHEMBL19072617 | 0.69 | PIK3CD (0.45) | PIK3CDPIK3R1PIK3CGPIK3CBPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017133655-A1 | BENZOTHIAZINE AND BENZOTHIADIAZINE COMPOUNDS AND PREPARATION AND USE | 浙江大学 | 2017-08-10 | — | — | WO | disclosed |