⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19251731 | 1.00 | — | — | |
| SCHEMBL19275893 | 1.00 | — | — | |
| SCHEMBL19277782 | 1.00 | — | — | |
| SCHEMBL17525227 | 1.00 | — | — | |
| SCHEMBL19277501 | 1.00 | — | — | |
| SCHEMBL19277878 | 1.00 | — | — | |
| SCHEMBL19277784 | 0.78 | MEN1 (0.31) | — | |
| SCHEMBL7738490 | 0.71 | SMN1; SMN2 (0.30) | — | |
| SCHEMBL16204346 | 0.67 | — | — | |
| SCHEMBL2349091 | 0.65 | ATM (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10793581-B2 | Stereochemically defined polypropionates and methods for making and using the same | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2020-10-06 | — | — | US | claimed |
| US-10160768-B2 | Stereochemically defined polypropionates and methods for making and using the same | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2018-12-25 | — | — | US | claimed |
| US-20170240560-A1 | STEREOCHEMICALLY DEFINED POLYPROPIONATES AND METHODS FOR MAKING AND USING THE SAME | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2017-08-24 | — | — | US | claimed |
| US-10793581-B2 | Stereochemically defined polypropionates and methods for making and using the same | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2020-10-06 | — | — | US | disclosed |
| US-20200055866-A1 | STEREOCHEMICALLY DEFINED POLYPROPIONATES AND METHODS FOR MAKING AND USING THE SAME | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2020-02-20 | — | — | US | disclosed |
| US-10407439-B2 | Stereochemically defined polypropionates and methods for making and using the same | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2019-09-10 | — | — | US | disclosed |
| US-10160768-B2 | Stereochemically defined polypropionates and methods for making and using the same | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2018-12-25 | — | — | US | disclosed |
| US-20180186810-A1 | STEREOCHEMICALLY DEFINED POLYPROPIONATES AND METHODS FOR MAKING AND USING THE SAME | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2018-07-05 | — | — | US | disclosed |
| US-20170240560-A1 | STEREOCHEMICALLY DEFINED POLYPROPIONATES AND METHODS FOR MAKING AND USING THE SAME | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2017-08-24 | — | — | US | disclosed |