SCHEMBL1925261

SCHEMBL1925261

CC(=O)c1cccc(NC(=O)CCCl)c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 8/20 0.62
ALDH1A1 P00352 6/20 0.62
MEN1 O00255 5/20 0.62
MAPT P10636 3/20 0.62
RAB9A P51151 1/20 0.62
CYP1A2 P05177 1/20 0.62
CYP3A4 P08684 1/20 0.62
CYP2C9 P11712 1/20 0.62
CYP2C19 P33261 1/20 0.62
SMN1; SMN2 Q16637 1/20 0.62
HPGD P15428 1/20 0.59
GAA P10253 1/20 0.59
TP53 P04637 1/20 0.59
RXFP1 Q9HBX9 1/20 0.59
HTT P42858 2/20 0.58
LMNA P02545 1/20 0.58
TDP1 Q9NUW8 2/20 0.57
NPC1 O15118 1/20 0.57
PARP1 P09874 1/20 0.57
PARP10 Q53GL7 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2645244 0.91 KMT2A (0.66) KMT2AALDH1A1MEN1MAPTRAB9A
SCHEMBL6272750 0.89 HPGD (0.74) KMT2AALDH1A1MEN1MAPTRAB9A
SCHEMBL5974722 0.87 PARP1 (0.73) KMT2AALDH1A1MEN1MAPTRAB9A
SCHEMBL27861904 0.87 KMT2A (0.60) KMT2AALDH1A1MEN1MAPTRAB9A
SCHEMBL19976712 0.85 KMT2A (0.63) KMT2AALDH1A1MEN1MAPTRAB9A
SCHEMBL11989153 0.85 KMT2A (0.71) KMT2AALDH1A1MEN1MAPTRAB9A
SCHEMBL11989152 0.85 KMT2A (0.71) KMT2AALDH1A1MEN1MAPTRAB9A
SCHEMBL13480137 0.84 SMN1; SMN2 (0.67) KMT2AALDH1A1MEN1MAPTRAB9A
SCHEMBL4927360 0.84 KMT2A (0.66) KMT2AALDH1A1MEN1MAPTRAB9A
SCHEMBL27674139 0.83 KMT2A (0.64) KMT2AALDH1A1MEN1MAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9738064-B2 Lithographic printing plate precursor AGFA GRAPHICS N.V. (BE) 2017-08-22 US disclosed
US-9738064-B2 Lithographic printing plate precursor AGFA GRAPHICS N.V. (BE) 2017-08-22 US disclosed
US-20120266768-A1 Lithographic Printing Plate Precursor AGFA GRAPHICS NV (BE) 2012-10-25 US disclosed
US-20120266768-A1 Lithographic Printing Plate Precursor AGFA GRAPHICS NV (BE) 2012-10-25 US disclosed
EP-2329951-B1 A lithographic printing plate precursor AGFA GRAPHICS NV (BE) 2012-06-20 EP disclosed
WO-2011067382-A1 A LITHOGRAPHIC PRINTING PLATE PRECURSOR AGFA GRAPHICS NV (BE) 2011-06-09 WO disclosed
WO-2011067382-A1 A LITHOGRAPHIC PRINTING PLATE PRECURSOR AGFA GRAPHICS NV (BE) 2011-06-09 WO disclosed
EP-2329951-A1 A lithographic printing plate precursor AGFA Graphics NV (BE) 2011-06-08 EP disclosed