Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.32 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.31 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.31 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21779886 | 0.80 | HRH3 (0.36) | DPP4DPP8DPP9GNAI3GNAO1 | |
| SCHEMBL16249373 | 0.75 | HRH4 (0.33) | — | |
| SCHEMBL2428595 | 0.74 | — | — | |
| SCHEMBL1306188 | 0.74 | — | — | |
| SCHEMBL680926 | 0.74 | — | — | |
| SCHEMBL23334406 | 0.74 | HRH3 (0.33) | — | |
| Hydrochloric Acid SCHEMBL2430335 | 0.73 | HRH4 (0.33) | GNAI3GNAO1GNAI1 | |
| Hydrochloric Acid SCHEMBL2429996 | 0.73 | HRH4 (0.33) | GNAI3GNAO1GNAI1 | |
| Hydrochloric Acid SCHEMBL4702852 | 0.73 | HRH4 (0.33) | GNAI3GNAO1GNAI1 | |
| Hydrochloric Acid SCHEMBL2157658 | 0.73 | HRH4 (0.33) | GNAI3GNAO1GNAI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9732083-B2 | Tricyclic gyrase inhibitors | MERCK SHARP & DOHME CORP. (US) | 2017-08-15 | — | — | US | disclosed |