Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 19/20 | 0.65 |
| ▸ | PIK3R1 | P27986 | 18/20 | 0.65 |
| ▸ | PIK3CB | P42338 | 8/20 | 0.56 |
| ▸ | PIK3CG | P48736 | 8/20 | 0.56 |
| ▸ | PIK3CA | P42336 | 6/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19252618 | 1.00 | PIK3CD (0.65) | PIK3CDPIK3R1PIK3CBPIK3CGPIK3CA | |
| SCHEMBL19252987 | 0.89 | PIK3CD (0.65) | PIK3CDPIK3R1PIK3CBPIK3CGPIK3CA | |
| SCHEMBL19251626 | 0.89 | PIK3CD (0.65) | PIK3CDPIK3R1PIK3CBPIK3CGPIK3CA | |
| SCHEMBL19251634 | 0.86 | PIK3R1 (0.62) | PIK3CDPIK3R1PIK3CBPIK3CGPIK3CA | |
| SCHEMBL19252617 | 0.86 | PIK3R1 (0.62) | PIK3CDPIK3R1PIK3CBPIK3CGPIK3CA | |
| SCHEMBL19251464 | 0.80 | PIK3CD (0.58) | PIK3CDPIK3R1PIK3CBPIK3CGPIK3CA | |
| SCHEMBL19252619 | 0.79 | PIK3CD (0.68) | PIK3CDPIK3R1PIK3CBPIK3CGPIK3CA | |
| SCHEMBL19251399 | 0.79 | PIK3R1 (1.00) | PIK3CDPIK3R1PIK3CBPIK3CGPIK3CA | |
| SCHEMBL19251608 | 0.79 | PIK3CD (0.68) | PIK3CDPIK3R1PIK3CBPIK3CGPIK3CA | |
| SCHEMBL19251471 | 0.79 | PIK3CD (0.54) | PIK3CDPIK3R1PIK3CBPIK3CGPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017133655-A1 | BENZOTHIAZINE AND BENZOTHIADIAZINE COMPOUNDS AND PREPARATION AND USE | 浙江大学 | 2017-08-10 | — | — | WO | disclosed |