Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 18/20 | 0.46 |
| ▸ | PIK3R1 | P27986 | 11/20 | 0.46 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.41 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 4/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.39 |
| ▸ | EGFR | P00533 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19251448 | 1.00 | PIK3CD (0.46) | PIK3CDPIK3R1PIK3CGPIK3C3PIK3CB | |
| SCHEMBL19251431 | 0.95 | PIK3CD (0.41) | PIK3CDPIK3R1PIK3CGPIK3C3PIK3CB | |
| SCHEMBL19254004 | 0.95 | PIK3CD (0.41) | PIK3CDPIK3R1PIK3CGPIK3C3PIK3CB | |
| SCHEMBL19254006 | 0.93 | PIK3CD (0.41) | PIK3CDPIK3R1PIK3CGPIK3C3PIK3CB | |
| SCHEMBL19251441 | 0.93 | PIK3CD (0.41) | PIK3CDPIK3R1PIK3CGPIK3C3PIK3CB | |
| SCHEMBL19254018 | 0.90 | PIK3CD (0.42) | PIK3CDPIK3R1PIK3CGPIK3C3PIK3CB | |
| SCHEMBL19251449 | 0.90 | PIK3CD (0.42) | PIK3CDPIK3R1PIK3CGPIK3C3PIK3CB | |
| SCHEMBL19252983 | 0.86 | PIK3CD (0.46) | PIK3CDPIK3R1PIK3CGPIK3CBPIK3CA | |
| SCHEMBL19254001 | 0.83 | PIK3R1 (0.48) | PIK3CDPIK3R1PIK3CGPIK3CBPIK3CA | |
| SCHEMBL19251442 | 0.83 | PIK3R1 (0.48) | PIK3CDPIK3R1PIK3CGPIK3CBPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017133655-A1 | BENZOTHIAZINE AND BENZOTHIADIAZINE COMPOUNDS AND PREPARATION AND USE | 浙江大学 | 2017-08-10 | — | — | WO | disclosed |