Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 19/20 | 0.44 |
| ▸ | PIK3R1 | P27986 | 13/20 | 0.44 |
| ▸ | PIK3CB | P42338 | 6/20 | 0.44 |
| ▸ | PIK3CG | P48736 | 6/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19251402 | 1.00 | PIK3CD (0.44) | PIK3CDPIK3R1PIK3CBPIK3CGPIK3CA | |
| SCHEMBL19251451 | 0.90 | PIK3CD (0.39) | PIK3CDPIK3R1PIK3CBPIK3CGPIK3CA | |
| SCHEMBL19254022 | 0.90 | PIK3CD (0.39) | PIK3CDPIK3R1PIK3CBPIK3CGPIK3CA | |
| SCHEMBL19252665 | 0.90 | PIK3R1 (0.54) | PIK3CDPIK3R1PIK3CBPIK3CGPIK3CA | |
| SCHEMBL19251460 | 0.90 | PIK3R1 (0.54) | PIK3CDPIK3R1PIK3CBPIK3CGPIK3CA | |
| SCHEMBL19251418 | 0.84 | PIK3CD (0.45) | PIK3CDPIK3R1PIK3CBPIK3CGPIK3CA | |
| SCHEMBL19254008 | 0.84 | PIK3CD (0.45) | PIK3CDPIK3R1PIK3CBPIK3CGPIK3CA | |
| SCHEMBL19251409 | 0.84 | PIK3CD (0.46) | PIK3CDPIK3R1PIK3CBPIK3CGPIK3CA | |
| SCHEMBL19252975 | 0.84 | PIK3CD (0.46) | PIK3CDPIK3R1PIK3CBPIK3CGPIK3CA | |
| SCHEMBL19254007 | 0.83 | PIK3CD (0.59) | PIK3CDPIK3R1PIK3CBPIK3CGPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017133655-A1 | BENZOTHIAZINE AND BENZOTHIADIAZINE COMPOUNDS AND PREPARATION AND USE | 浙江大学 | 2017-08-10 | — | — | WO | disclosed |