Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23942195 | 0.77 | ERBB2 (0.33) | ERBB2 | |
| SCHEMBL11881192 | 0.77 | LRRK2 (0.38) | LRRK2DYRK1AKDM4EHTTALDH1A1 | |
| SCHEMBL10749916 | 0.75 | — | — | |
| SCHEMBL15666218 | 0.74 | ERBB2 (0.32) | ERBB2DYRK1AHTT | |
| SCHEMBL24533909 | 0.74 | ERBB2 (0.36) | LRRK2ERBB2DYRK1AKDM4EALDH1A1 | |
| SCHEMBL29395633 | 0.74 | PDPK1 (0.34) | LRRK2DYRK1AKDM4EALDH1A1LMNA | |
| SCHEMBL29207909 | 0.71 | USP8 (0.33) | ERBB2KDM4EALDH1A1LMNAGAA | |
| SCHEMBL19917172 | 0.70 | — | — | |
| SCHEMBL12186825 | 0.70 | LRRK2 (0.47) | LRRK2DYRK1AKDM4EHTTALDH1A1 | |
| SCHEMBL29588388 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017133655-A1 | BENZOTHIAZINE AND BENZOTHIADIAZINE COMPOUNDS AND PREPARATION AND USE | 浙江大学 | 2017-08-10 | — | — | WO | disclosed |