Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 13/20 | 0.72 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.63 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | ESR1 | P03372 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19254349 | 0.91 | CSNK2A1 (0.84) | CSNK2A1CSNK2A2CSNK2BKDM4EALDH1A1 | |
| SCHEMBL19207471 | 0.87 | CSNK2A1 (0.69) | CSNK2A1CSNK2A2CSNK2BKDM4EALDH1A1 | |
| SCHEMBL19254350 | 0.86 | CSNK2A1 (0.67) | CSNK2A1CSNK2A2CSNK2BKDM4EALDH1A1 | |
| SCHEMBL298156 | 0.86 | CSNK2A1 (0.85) | CSNK2A1CSNK2A2CSNK2BKDM4EALDH1A1 | |
| SCHEMBL19254305 | 0.83 | CSNK2A1 (0.70) | CSNK2A1CSNK2A2CSNK2BKDM4EALDH1A1 | |
| SCHEMBL19254353 | 0.82 | CSNK2A1 (0.78) | CSNK2A1CSNK2A2CSNK2BKDM4EALDH1A1 | |
| SCHEMBL296461 | 0.81 | KDM4E (0.81) | CSNK2A1CSNK2A2CSNK2BKDM4EALDH1A1 | |
| SCHEMBL297749 | 0.81 | CSNK2A1 (0.87) | CSNK2A1KDM4EUSP2LMNATSHR | |
| SCHEMBL3333973 | 0.80 | CSNK2A1 (0.84) | CSNK2A1CSNK2A2CSNK2BKDM4EALDH1A1 | |
| SCHEMBL19254359 | 0.80 | CSNK2A1 (0.67) | CSNK2A1CSNK2A2CSNK2BKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017136689-A1 | PURINE COMPOUNDS POSSESSING ANTICANCER ACTIVITY | ACADEMIA SINICA (TW) | 2017-08-10 | — | — | WO | disclosed |